The plot follows the story of WilPharma the new pharmaceutical company supposedly responsible for the new outbreak of the T-Virus in India and now in an airport where Claire is initially trapped until her reunion with Leon. The movie continues in WilPharma facilities (similar to the way Resident Evil 2 concludes at Umbrella's facilities) with a case of infection of the G-Virus. The movie stars the main characters of 2 disc game - Resident Evil 2 - Claire Redfield and Leon S. Kennedy (also staring in Resident Evil 4) the original survivors of Raccoon City.